It’s European Antibiotic Awareness Day today, and the MRC, BBSRC and EPSRC have produced a new timeline looking at progress in tackling antibiotic resistance over the past few decades. Here we’ve picked just four examples ― from glowing infections to a smartphone app ― reflecting the four themes of a cross-research council antimicrobial resistance funding call to give you a taster of research in this area.
Germs that glow
Being able to observe how bacteria and other bugs move around the body is crucial to knowing how to tackle them. In an MRC-funded study, Professor Gad Frankel at Imperial College London developed a way to infect mice with Citrobacter rodentium bacteria that had been genetically modified to produce light.  His team could then track this glowing infection around the mouse’s body in real time, and regular CT scans showed how different vaccines and antibiotics change the way bacteria take over parts of the body. Read more