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Posts tagged ‘Mouse model’

Profile: Qing-Jun Meng

Qing-Jun Meng

Qing-Jun Meng

Qing-Jun Meng is an MRC fellow at the University of Manchester. He told Katherine Nightingale about his research into biological clocks, their role in age-associated conditions, and how they offer a whole new way of looking at disease.

How does a Chinese flight surgeon end up researching biological clocks in Manchester? In the early 2000s, Qing-Jun Meng was advising pilots and medical officers for astronauts in China’s burgeoning space programme. Now he’s halfway through an MRC fellowship researching how changes in the body’s circadian rhythm during ageing cause disease.

The two fields aren’t actually so different, says Qing-Jun. “It sounds like discipline hopping but some of the lectures I gave to pilots were about body clocks and jet lag. That was when I first got interested in the field.”

Frustrated by the lack of opportunity to do cutting edge research, particularly that which would benefit people, Qing-Jun began applying for postdoc jobs abroad. His acceptance to work in vascular tissue engineering at Manchester Royal Infirmary was the first step; a second step just down the road to the University of Manchester landed him in biological clocks, where he’s remained ever since. Read more

Profile: Steve Brown

Steve Brown (Credit: Noel Murphy)

Steve Brown (Image copyright: Noel Murphy)

Professor Steve Brown heads up the MRC Mammalian Genetics Unit (MGU) at MRC Harwell, which focuses on using the mouse as a model for human disease. Katherine Nightingale spoke to Steve about the international nature of mouse genetics and his own research that looks at the genes behind deafness.

Professor Steve Brown has an open door policy. “I think it’s absolutely critical for a director to be approachable. I also like to go round talking to people in the lab, finding out how the scientists are getting on,” he says.

Since becoming director in 1996, Steve has been putting his open door policy to good use, increasingly steering the unit towards international collaboration, a vital part of modern mammalian genetics.

“Many of the challenges we have in genetics right now can’t be addressed by just one institute, we need to work in large collaborative enterprises, often internationally,” says Steve. Read more