For the first time, after eight years of collaborative work, results are published in Lancet Infectious Disease describing the positive impact of the introduction of pneumococcal conjugate vaccines in a low-income country. But how do you go about measuring this ‘impact’? Principal Investigator of the Pneumococcal Surveillance Project at MRC Unit, The Gambia, Dr Grant Mackenzie, explains the human resource required for large-scale disease surveillance in rural Africa, the challenges and the rewards.
Pneumococcal disease is caused by a bacterium known as Streptococcus pneumoniae. Symptoms range from sinus and ear infections to pneumonia, bloodstream infections, and meningitis. The pneumococcus bacteria cause more deaths in children worldwide than any other single microorganism and those in low-income countries are particularly at risk.
MRC Unit, The Gambia has conducted pneumococcal research for over two decades. It started with a disease burden study in 1989, in the Basse area in the rural east of The Gambia, which established the substantial burden of invasive pneumococcal disease.