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Posts tagged ‘International Mouse Phenotyping Consortium’

New tools help show what genes do

To understand the roles of different genes, Dr James Brown and colleagues at the MRC Harwell Institute are part of a project trying to find out what every single mouse gene does. To help speed things along, they have developed new software to analyse images of mouse embryos.

black mouse
Our 20,000 genes provide the instructions for everything our body does. But we don’t yet know what each one is responsible for. We share 90 percent of our genes with mice so finding out their ‘function’ could help us understand more about human disease. Read more

Profile: Steve Brown

Steve Brown (Credit: Noel Murphy)

Steve Brown (Image copyright: Noel Murphy)

Professor Steve Brown heads up the MRC Mammalian Genetics Unit (MGU) at MRC Harwell, which focuses on using the mouse as a model for human disease. Katherine Nightingale spoke to Steve about the international nature of mouse genetics and his own research that looks at the genes behind deafness.

Professor Steve Brown has an open door policy. “I think it’s absolutely critical for a director to be approachable. I also like to go round talking to people in the lab, finding out how the scientists are getting on,” he says.

Since becoming director in 1996, Steve has been putting his open door policy to good use, increasingly steering the unit towards international collaboration, a vital part of modern mammalian genetics.

“Many of the challenges we have in genetics right now can’t be addressed by just one institute, we need to work in large collaborative enterprises, often internationally,” says Steve. Read more