MRC Senior Non-Clinical Research Fellow Dr Eva Hoffmann is trying to find why a woman’s risk of having a baby with a chromosomal disorder – such as Down syndrome – increases with age. Here she tells us about her working life.
I started my own lab after quite a short postdoc – three years – when I was awarded my Royal Society fellowship. I undertook this at the MRC Genome Damage and Stability Centre, now embedded within the University of Sussex. I’ve been an MRC Senior Non-Clinical Research Fellow for four years and that’s really allowed me to do more blue skies research that is paying dividends now.
I’m interested in understanding how the information encoded in our genomes and chromosomes is transmitted accurately to the next generation. For human health this is very important because there’s a high level of pregnancy loss associated particularly with a woman’s age. Today, more women over 30 are giving birth than in past generations – in the UK, women 35 and older account for around 20 per cent of all births. Read more