To understand the roles of different genes, Dr James Brown and colleagues at the MRC Harwell Institute are part of a project trying to find out what every single mouse gene does. To help speed things along, they have developed new software to analyse images of mouse embryos.
Our 20,000 genes provide the instructions for everything our body does. But we don’t yet know what each one is responsible for. We share 90 percent of our genes with mice so finding out their ‘function’ could help us understand more about human disease. Read more
Today, the UK Biobank has launched the largest body scanning project in the world. Funded by the MRC, Wellcome Trust and British Heart Foundation, the biobank will scan 100,000 people to provide images of their brains, hearts, bones, carotid arteries and abdominal fat. Head of the Division of Brain Sciences at Imperial College London Professor Paul Matthews is one of the academic experts who have been supporting UK Biobank to create this resource and he tells us how it could prove invaluable to all areas of medicine.
Building the bank
Over 10 years, the UK Biobank has recruited and gathered a wealth of high quality information from 500,000 people across the country. These people have donated blood, urine and saliva samples, provided detailed health, lifestyle and environment information and agreed to allow the biobank to follow their GP and hospital records throughout life.
Now we will be adding sophisticated imaging to enrich our understanding of the origins and progression of the major diseases of later life. Read more