Bacteria resistant to drugs are stopping us from treating infectious diseases and undermining medical advances. So what can we do about it? ThisWHO Antibiotic Awareness WeekDrJonathan Pearce, Head of Infections and Immunity at the MRC, explains why understanding how resistance develops and spreads is key to tackling antibiotic resistance. And how using this knowledge, we can find creative new ways of preventing and treating infections.
Enterobacteria grown on a selective agar plate.
Antibiotic resistance is now recognised as one of the most serious threats to human health, spreading across national boundaries. It arises from a complex interplay between biomedical, animal, social, cultural and environmental factors. If we are to meet this challenge, we need to take both an international and interdisciplinary approach.
To improve the outlook for patients with life-threatening fungal disease, we need a coordinated approach to tackle the infections. That’s why we set up the MRC Centre for Medical Mycology (MRC CMM) with the University of Aberdeen last year. Here Masters students Joanne Calley, Emily Speakman, Catherine Mark and Alexander Currie share five reasons why they chose to study fungi and are excited to be working at the forefront of fungal diseases research.
Fluorescent stain of zinc (blue) in Candida albicans cells (red)
Last year a UK-China research collaboration took an unexpected turn following the discovery of resistance to the ‘last resort’ antibiotic: colistin. Here Professor Timothy Walsh, Professor of Medical Microbiology at Cardiff University, describes how the global community can learn from the positive steps taken by the Chinese Government.
Antibiotic resistance is really all about people and society. We often blame antimicrobial resistance on the bug and how resistance can travel from one bug to another. But different sectors, for example farming, hospitals and communities, are all critically linked.