Charity partners Alzheimer’s Society and Alzheimer’s Research UK will be instrumental in involving people living with dementia in the work of the new £250m MRC-led UK Dementia Research Institute. Here Alzheimer’s Society Ambassador Keith Oliver shares his hopes for how the new institute will make life better for people with dementia, now and tomorrow.
Photo copyright: Alzheimer’s Society
My world changed in 2010 when I was diagnosed with early-onset Alzheimer’s disease at the age of 55. My early symptoms were falling over, an element of reduced concentration and being unable to follow things as well as I did previously.
I went to the GP thinking I’d got an ear infection and was sent for an MRI scan. When I had an appointment with a neurologist to discuss the scan he said, totally out of the blue, that it looked like the early stages of Alzheimer’s disease. After attending a memory clinic for around four months of quite intensive testing and assessments I received a diagnosis. Read more
This image has been created by a team at the MRC Laboratory of Molecular Biology (MRC LMB) in collaboration with the University of Exeter and Birkbeck College and, for the first time, shows a detailed structure of a ‘lysenin pore’. Dr Christos Savva, an Electron Microscopy Facility scientist at the MRC LMB spoke to Sylvie Kruiniger about why understanding these structures could be the key to treating many different diseases.
It may look like some kind of technicolour mushroom but this teeny structure is actually a cell-attacking pore made of just nine proteins.
Conservators Rebecca Bennett and Jill Barnard tell us about their project, funded by PRISM, to conserve 150 items from the Crick Mill Hill Laboratory (previously the MRC National Institute for Medical Research, NIMR) in preparation for the move to the Francis Crick Institute. The objects will be used by the Crick for exhibition and may also be loaned to education groups with an interest in the history of biomedical research.
Polystyrene proteins: This early model of a ribosome designed by Robert Cox and built by NIMR engineer Frank Doré in 1968 was signed by some of the leading biomedical scientists of the time – including Francis Crick.
We are now 11 weeks into our ‘Tools of the Trade’ conservation project. So far we have treated 137 of 150 historical objects that tell the story of how research developed at NIMR over the course of 100 years. Read more